What is TULSA


The main objective of the TULSA treatment is to kill diseased prostate tissue while protecting the surrounding organs and structures, better maintaining the functions of those organs and structures when it comes to potency and continence.

 

What does TULSA stand for?


TULSA stands for Transurethral Ultrasound Ablation of the Prostate. The therapy treatment is performed in combination with real-time MR Imaging, thermal Ultrasound and a closed-loop temperature feedback control. As such it is performed in an MRI examination room and not in an operating theatre.

The Steps of Treatment

 
 

Potential Benefits and Advantages

Radiation-Free
The TULSA procedure does not use ionising radiation. It is using High Intensity Therapeutic Ultrasound.
Incision-Free
TULSA is a minimal invasive procedure and requires no incision to be made. Most patients recover quickly and can return to their normal everyday life after a few days.
Customised Treatment
Option of focal or whole gland treatment depending on the location and size of the tumour.
Outpatient Procedure
Following a TULSA procedure, the patient is usually discharged from the hospital the same day, or the next day depending on the doctor’s assessment.
Treatment - firstline or subsequent
In addition firstline treatment, TULSA can be performed as a subsequent treatment option for prostate cancer if radiation therapy has shown to be unsuccessful.
Quality of Life
Most patients maintain their erectile and urinary function; unlike for some of the other treatments.⁴ A patients ability to maintain erectile function following a TULSA depends on many factors (stage and category). The procedure is generally well-tolerated, meaning it gives patients the chance to lead a normal, high-quality life after the treatment.
Predictable Tissue Ablation
Clinical evidence has shown that neighbouring organs such as the rectum are not affected by the TULSA procedure. The system directs the ultrasound energy towards the areas of the prostate the doctor plans to treat, and actively protects the areas not to be treated.⁵
 

How long does the treatment take?


The treatment is performed in a single session that takes a few hours. It is usually conducted under general anesthesia. After the treatment, the doctor may decide to keep the patient in the hospital overnight for observation or the patient may go home the same day.

Do I qualify for a TULSA?


The TULSA procedure has been developed for patients with localised tumours (cancer restricted/limited to the prostate). Patients with low to intermediate risk prostate cancer may benefit from the TULSA procedure. Topline results of the performed clinical trial for patients with Gleason scores 6 and 7 has been announced on April 4, 2019.⁶

Whether or not you will qualify for a TULSA will be decided by the treating Physician.
 

First TULSA Treatment at LHSC and 2nd treated Patient

“Everything has returned to normal and in some cases is better that what it has been for five years.” ⁷

Brian

Joseph Chin MD, FRCSC and his first TULSA patient Brian (Treatment in London, ON, Canada - 2013)

Looking for a
Treatment Centre?


There are several hospitals that are offering a TULSA in Europe.
Find out out more about each centre following the link.


Treatment Centres
⁴Joseph Chin et al. (2016): MAGNETIC RESONANCE IMAGING-GUIDED TRANSURETHRAL ULTRASOUND ABLATION OF PROSTATE TISSUE IN PATIENTS WITH LOCALIZED PROSTATE CANCER: A PROSPECTIVE PHASE 1 CLINICAL TRIAL, In: European Urology, 70(3).
⁵ Laurence Klotz et al. (2018): LBA20 MRI-GUIDED TRANSURETHRAL ULTRASOUND ABLATION (TULSA) IN PATIENTS WITH LOCALIZED PROSTATE CANCER: PRELIMINARY RESULTS OF TACT PIVOTAL STUDY, In: The Journal of Urology, 199(4):e1077-e1078.
⁶ https://www.globenewswire.com/news-release/2019/04/04/1797449/0/en/Profound-Medical-Announces-Positive-Topline-Results-from-TACT-Pivotal-Clinical-Trial-of-TULSA-PRO-in-Patients-with-Prostate-Cancer.html, May 2019.
⁷ https://www.lhsc.on.ca/news/lhsc-and-lawson-announce-world-first-treatment-of-localized-prostate-cancer.